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Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling

BACKGROUND: Previous studies had showed that Apelin 13 could protect against apoptosis induced by ischemic/reperfusion (I/R). However, the mechanisms whereby Apelin 13 protected brain I/R remained to be elucidated. The present study was designed to determine whether Apelin 13 provided protection thr...

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Detalles Bibliográficos
Autores principales: Duan, Jialin, Cui, Jia, Yang, Zhifu, Guo, Chao, Cao, Jinyi, Xi, Miaomiao, Weng, Yan, Yin, Ying, Wang, Yanhua, Wei, Guo, Qiao, Boling, Wen, Aidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357442/
https://www.ncbi.nlm.nih.gov/pubmed/30709405
http://dx.doi.org/10.1186/s12974-019-1406-7