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SOX2 interferes with the function of CDX2 in bile acid-induced gastric intestinal metaplasia

BACKGROUND: Intestinal metaplasia (IM) is a premalignant lesion associated with gastric cancer. Both animal and clinical studies have revealed that bile acid reflux and subsequent chronic inflammation are key causal factors of IM. Previous studies indicated that SOX2, the key transcription factor in...

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Detalles Bibliográficos
Autores principales:	Yuan, Ting, Ni, Zhen, Han, Chuan, Min, Yali, Sun, Nina, Liu, Caifang, Shi, Miao, Lu, Wenquan, Wang, Na, Du, Feng, Wu, Qiong, Xie, Ning, Shi, Yongquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357452/ https://www.ncbi.nlm.nih.gov/pubmed/30733645 http://dx.doi.org/10.1186/s12935-019-0739-8

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