Genomic instability in a chronic lymphocytic leukemia patient with mono-allelic deletion of the DLEU and RB1 genes

BACKGROUND: The most frequent cytogenetic abnormality detected in chronic lymphocytic leukemia (CLL) patients is the presence of a deletion within the chromosome band 13q14. Deletions can be heterogeneous in size, generally encompassing the DLEU1 and DLEU2 genes (minimal deleted region), but at time...

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Detalles Bibliográficos
Autores principales: Nava-Rodríguez, María Paulina, Domínguez-Cruz, Martín Daniel, Aguilar-López, Lilia Beatriz, Borjas-Gutiérrez, César, Magaña-Torres, María Teresa, González-García, Juan Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357463/
https://www.ncbi.nlm.nih.gov/pubmed/30733830
http://dx.doi.org/10.1186/s13039-019-0417-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357463/
https://www.ncbi.nlm.nih.gov/pubmed/30733830
http://dx.doi.org/10.1186/s13039-019-0417-5

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