Application of CRISPR-Cas12a temperature sensitivity for improved genome editing in rice, maize, and Arabidopsis

BACKGROUND: CRISPR-Cas12a (formerly Cpf1) is an RNA-guided endonuclease with distinct features that have expanded genome editing capabilities. Cas12a-mediated genome editing is temperature sensitive in plants, but a lack of a comprehensive understanding on Cas12a temperature sensitivity in plant cel...

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Detalles Bibliográficos
Autores principales: Malzahn, Aimee A., Tang, Xu, Lee, Keunsub, Ren, Qiurong, Sretenovic, Simon, Zhang, Yingxiao, Chen, Hongqiao, Kang, Minjeong, Bao, Yu, Zheng, Xuelian, Deng, Kejun, Zhang, Tao, Salcedo, Valeria, Wang, Kan, Zhang, Yong, Qi, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357469/
https://www.ncbi.nlm.nih.gov/pubmed/30704461
http://dx.doi.org/10.1186/s12915-019-0629-5

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