Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium

BACKGROUND & AIMS: Hypoxia-associated pathways influence the development of inflammatory bowel disease. Adaptive responses to hypoxia are mediated through hypoxia-inducible factors, which are regulated by iron-dependent hydroxylases. Signals reflecting oxygen tension and iron levels in enterocyt...

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Detalles Bibliográficos
Autores principales: Simmen, Simona, Cosin-Roger, Jesus, Melhem, Hassan, Maliachovas, Nikolaos, Maane, Max, Baebler, Katharina, Weder, Bruce, Maeyashiki, Chiaki, Spanaus, Katharina, Scharl, Michael, de Vallière, Cheryl, Zeitz, Jonas, Vavricka, Stephan R., Hausmann, Martin, Rogler, Gerhard, Ruiz, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357696/
https://www.ncbi.nlm.nih.gov/pubmed/30704983
http://dx.doi.org/10.1016/j.jcmgh.2018.10.006

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