Cargando…

The CCR2(+) Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) typically arises in fibrotic or cirrhotic livers, which are characterized by pathogenic angiogenesis. Myeloid immune cells, specifically tumor-associated macrophages (TAMs), may represent potential novel therapeutic targets in HCC, complementing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bartneck, Matthias, Schrammen, Peter L., Möckel, Diana, Govaere, Olivier, Liepelt, Anke, Krenkel, Oliver, Ergen, Can, McCain, Misti Vanette, Eulberg, Dirk, Luedde, Tom, Trautwein, Christian, Kiessling, Fabian, Reeves, Helen, Lammers, Twan, Tacke, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357791/ https://www.ncbi.nlm.nih.gov/pubmed/30704985 http://dx.doi.org/10.1016/j.jcmgh.2018.10.007

Ejemplares similares

Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury
por: Puengel, Tobias, et al.
Publicado: (2017)

Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion
por: Bartneck, Matthias, et al.
Publicado: (2020)

Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults
por: Seidler, Sebastian, et al.
Publicado: (2010)

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance
por: Gautheron, Jérémie, et al.
Publicado: (2016)

Automated Generation of Reliable Blood Velocity Parameter Maps from Contrast-Enhanced Ultrasound Data
por: Theek, Benjamin, et al.
Publicado: (2017)

Differential Gene Expression in Circulating CD14(+) Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis
por: Liepelt, Anke, et al.
Publicado: (2020)

Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis
por: Schon, Hans-Theo, et al.
Publicado: (2016)

Neutrophils are a main source of circulating suPAR predicting outcome in critical illness
por: Gussen, Hendrik, et al.
Publicado: (2019)

Correction to: Neutrophils are a main source of circulating suPAR predicting outcome in critical illness
por: Gussen, Hendrik, et al.
Publicado: (2019)

Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis
por: Krenkel, Oliver, et al.
Publicado: (2019)

Risk of falls in postmenopausal women treated with romosozumab: Preliminary indices from a meta-analysis of randomized, controlled trials
por: Möckel, Luis, et al.
Publicado: (2020)

Nanomedicine formulations for combination therapies
por: Lammers, Twan, et al.
Publicado: (2010)

A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis
por: Gautheron, Jérémie, et al.
Publicado: (2014)

Key features of the environment promoting liver cancer in the absence of cirrhosis
por: Zaki, Marco Youssef William, et al.
Publicado: (2021)

Circulating MicroRNA-223 Serum Levels Do Not Predict Sepsis or Survival in Patients with Critical Illness
por: Benz, Fabian, et al.
Publicado: (2015)

Riboflavin-Targeted Drug Delivery
por: Darguzyte, Milita, et al.
Publicado: (2020)

Imaging-assisted anticancer nanotherapy
por: Dasgupta, Anshuman, et al.
Publicado: (2020)

Cell-free DNA TAPS provides multimodal information for early cancer detection
por: Siejka-Zielińska, Paulina, et al.
Publicado: (2021)

Impact of retrotransposon protein L1 ORF1p expression on oncogenic pathways in hepatocellular carcinoma: the role of cytoplasmic PIN1 upregulation
por: Zadran, Bassier, et al.
Publicado: (2023)

Clinical translation of gold nanoparticles
por: Zhang, Rui, et al.
Publicado: (2022)

CX(3)CR1 Mediates the Development of Monocyte-Derived Dendritic Cells during Hepatic Inflammation
por: Sutti, Salvatore, et al.
Publicado: (2019)

Radiomic analysis of contrast-enhanced ultrasound data
por: Theek, Benjamin, et al.
Publicado: (2018)

Adapted Immune Responses of Myeloid-Derived Cells in Fatty Liver Disease
por: Hundertmark, Jana, et al.
Publicado: (2018)

Mouse models of hepatocarcinogenesis: What can we learn for the prevention of human hepatocellular carcinoma?
por: Vucur, Mihael, et al.
Publicado: (2010)

CCR2 inhibition sequesters multiple subsets of leukocytes in the bone marrow
por: Fujimura, Naoki, et al.
Publicado: (2015)

Targeting Activated Hepatic Stellate Cells Using Collagen-Binding Chitosan Nanoparticles for siRNA Delivery to Fibrotic Livers
por: Azzam, Menna, et al.
Publicado: (2020)

Isolation and Time Lapse Microscopy of Highly Pure Hepatic Stellate Cells
por: Bartneck, Matthias, et al.
Publicado: (2015)

Prognostic Relevance of Altered Lymphocyte Subpopulations in Critical Illness and Sepsis
por: Hohlstein, Philipp, et al.
Publicado: (2019)

Erratum: Hohlstein, P. et al. Prognostic Relevance of Altered Lymphocyte Subpopulations in Critical Illness and Sepsis. Journal of Clinical Medicine 2019, 8, 353
por: Hohlstein, Philipp, et al.
Publicado: (2019)

Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis
por: Zimmermann, Henning W., et al.
Publicado: (2011)

Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis
por: Roderburg, Christoph, et al.
Publicado: (2013)

Liver Fibrosis—From Mechanisms of Injury to Modulation of Disease
por: Liedtke, Christian, et al.
Publicado: (2022)

Imalytics Preclinical: Interactive Analysis of Biomedical Volume Data
por: Gremse, Felix, et al.
Publicado: (2016)

Hepatic C-X-C chemokine receptor type 6–expressing innate lymphocytes limit detrimental myeloid hyperactivation in acute liver injury
por: Heymann, Felix, et al.
Publicado: (2023)

Porcine monocyte subsets differ in the expression of CCR2 and in their responsiveness to CCL2
por: Moreno, Sara, et al.
Publicado: (2010)

CCR2 deficiency alters activation of microglia subsets in traumatic brain injury
por: Somebang, Kerri, et al.
Publicado: (2021)

Rare Pathogenic Variants Predispose to Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease
por: Pelusi, Serena, et al.
Publicado: (2019)

Rationale of using the dual chemokine receptor CCR2/CCR5 inhibitor cenicriviroc for the treatment of COVID-19
por: Files, Daniel Clark, et al.
Publicado: (2022)

An NF-kappaB- and IKK-Independent Function of NEMO Prevents Hepatocarcinogenesis by Suppressing Compensatory Liver Regeneration
por: Koppe, Christiane, et al.
Publicado: (2019)

Serum Levels of TNF Receptor Ligands Are Dysregulated in Sepsis and Predict Mortality in Critically Ill Patients
por: Roderburg, Christoph, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_sq69iudlno4gelcaicbvsr44dn