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Intestinal Lipolysis Mitigates Nonalcoholic Fatty Liver Disease: New Roles for Carboxylesterase 2c in the Intestine

The most important argument of this study is that modulation of intestinal lipid metabolism by enhancing intestinal Ces2c expression has the potential to affect hepatic and systemic lipid metabolism, regulating the development of NAFLD and systemic insulin resistance.

Detalles Bibliográficos
Autores principales: Pimienta, Michael, Beletsky, Alexander, Seki, Ekihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357825/
https://www.ncbi.nlm.nih.gov/pubmed/30766955
http://dx.doi.org/10.1002/hep4.1318
Descripción
Sumario:The most important argument of this study is that modulation of intestinal lipid metabolism by enhancing intestinal Ces2c expression has the potential to affect hepatic and systemic lipid metabolism, regulating the development of NAFLD and systemic insulin resistance.