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Reversing platinum resistance in ovarian cancer multicellular spheroids by targeting Bcl-2

PURPOSE: Peritoneal metastasis is the most common pathway for the spread of ovarian cancer. Ovarian cancer cells in ascites prefer to aggregate into the more chemoresistant multicellular spheroids (MCSs), leading to treatment failure and disease recurrence. We previously established a suspension MCS...

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Detalles Bibliográficos
Autores principales: Yang, Ya’nan, Li, Song, Sun, Yiting, Zhang, Di, Zhao, Zeyi, Liu, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357888/
https://www.ncbi.nlm.nih.gov/pubmed/30774376
http://dx.doi.org/10.2147/OTT.S187015