Cargando…
Reversing platinum resistance in ovarian cancer multicellular spheroids by targeting Bcl-2
PURPOSE: Peritoneal metastasis is the most common pathway for the spread of ovarian cancer. Ovarian cancer cells in ascites prefer to aggregate into the more chemoresistant multicellular spheroids (MCSs), leading to treatment failure and disease recurrence. We previously established a suspension MCS...
Autores principales: | Yang, Ya’nan, Li, Song, Sun, Yiting, Zhang, Di, Zhao, Zeyi, Liu, Lian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357888/ https://www.ncbi.nlm.nih.gov/pubmed/30774376 http://dx.doi.org/10.2147/OTT.S187015 |
Ejemplares similares
-
CDC25A Facilitates Chemo-resistance in Ovarian Cancer Multicellular Spheroids by Promoting E-cadherin Expression and Arresting Cell Cycles
por: Sun, Yiting, et al.
Publicado: (2019) -
The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance
por: Barbone, D, et al.
Publicado: (2011) -
Resistance to vincristine of human cells grown as multicellular spheroids.
por: Wibe, E.
Publicado: (1980) -
Unsuccessful mitosis in multicellular tumour spheroids
por: Molla, Annie, et al.
Publicado: (2017) -
Reversal of Anchorage-Independent Multicellular Spheroid into a Monolayer Mimics a Metastatic Model
por: Kunjithapatham, Rani, et al.
Publicado: (2014)