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The tumor suppressor p53 can promote collective cellular migration

Loss of function of the tumor suppressor p53 is known to increase the rate of migration of cells transiting the narrow pores of the traditional Boyden chamber assay. Here by contrast we investigate how p53 impacts the rate of cellular migration within a 2D confluent cell layer and a 3D collagen-embe...

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Detalles Bibliográficos
Autores principales:	He, Shijie, Carman, Christopher V., Lee, Jung Hyun, Lan, Bo, Koehler, Stephan, Atia, Lior, Park, Chan Young, Kim, Jae Hun, Mitchel, Jennifer A., Park, Jin-Ah, Butler, James P., Lu, Quan, Fredberg, Jeffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358060/ https://www.ncbi.nlm.nih.gov/pubmed/30707705 http://dx.doi.org/10.1371/journal.pone.0202065

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