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Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability

Genomic imprinting is important for normal brain development and aberrant imprinting has been associated with impaired cognition. We studied the imprinting status in selected imprints (H19, IGF2, SNRPN, PEG3, MEST1, NESPAS, KvDMR, IG-DMR and ZAC1) by pyrosequencing in blood samples from longitudinal...

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Detalles Bibliográficos
Autores principales:	Lorgen-Ritchie, Marlene, Murray, Alison D., Ferguson-Smith, Anne C., Richards, Marcus, Horgan, Graham W., Phillips, Louise H., Hoad, Gwen, Gall, Ishbel, Harrison, Kristina, McNeill, Geraldine, Ito, Mitsuteru, Haggarty, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358095/ https://www.ncbi.nlm.nih.gov/pubmed/30707743 http://dx.doi.org/10.1371/journal.pone.0211799

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