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Integrating predicted transcriptome from multiple tissues improves association detection

Integration of genome-wide association studies (GWAS) and expression quantitative trait loci (eQTL) studies is needed to improve our understanding of the biological mechanisms underlying GWAS hits, and our ability to identify therapeutic targets. Gene-level association methods such as PrediXcan can...

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Detalles Bibliográficos
Autores principales:	Barbeira, Alvaro N., Pividori, Milton, Zheng, Jiamao, Wheeler, Heather E., Nicolae, Dan L., Im, Hae Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358100/ https://www.ncbi.nlm.nih.gov/pubmed/30668570 http://dx.doi.org/10.1371/journal.pgen.1007889

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