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A study of affecting the recovery of Chinese patients with Bell palsy

We explored the risk factors for preventing recovery of Bell palsy (BP) in Chinese inpatients. Five hundred thirteen patients were included. The two end-points of assessment were the discharge and final follow-up results. Relationship between discharge and baseline: long patients delay (unhealed 4.0...

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Autores principales: Zhang, Hongbo, Du, Haixia, Qian, Mingjing, Wang, Yu, Zhou, Shenghua, Chen, Jing, Wan, Haitong, Yang, Jiehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358322/
https://www.ncbi.nlm.nih.gov/pubmed/30681613
http://dx.doi.org/10.1097/MD.0000000000014244
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author Zhang, Hongbo
Du, Haixia
Qian, Mingjing
Wang, Yu
Zhou, Shenghua
Chen, Jing
Wan, Haitong
Yang, Jiehong
author_facet Zhang, Hongbo
Du, Haixia
Qian, Mingjing
Wang, Yu
Zhou, Shenghua
Chen, Jing
Wan, Haitong
Yang, Jiehong
author_sort Zhang, Hongbo
collection PubMed
description We explored the risk factors for preventing recovery of Bell palsy (BP) in Chinese inpatients. Five hundred thirteen patients were included. The two end-points of assessment were the discharge and final follow-up results. Relationship between discharge and baseline: long patients delay (unhealed 4.03 ± 1.16 d vs improved 2.24 ± 1.0 d, P < .001), combined diseases (yes 77.06% vs no 86.71%, P = .01), and early use of acupuncture (yes 47.46% vs no 97.62%, P < .001) were bad factors. Therapeutic factors and discharge: only use of steroids was a positive factor (yes 92.54% vs no 57.30%, P < .001). Binary logistic regression found that early use of steroids was a favorable factor (P = .001), while early use of acupuncture (P < .001) and long patient delay (P < .001) were adverse factors. Subgroups analysis showed early use of steroids plus antivirals (steroids + antivirals vs antivirals + mecobalamin, P < .001) and early use of steroids plus mecobalamin were good choices (steroids + antivirals vs steroids + mecobalamin, P = .745), while early use of antivirals plus mecobalamin was a bad choice (vs other 2 groups, P < .001). Effect of drug dose and treatment course on discharge: long time use of steroids didn’t mean good efficacy (unhealed 10.80 ± 1.53 d vs improved 10.38 ± 1.21 d, P = .026). Final follow-up results: improved patients were better than that of unhealed at discharge (P < .001). Risk factors of discharge included long patient delay, combined diseases, and early use of acupuncture. Steroids plus antivirals or steroids plus mecobalamin were good choices for treatment. Long time use of steroids didn’t mean good effect. Improved patients at discharge had better results finally.
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spelling pubmed-63583222019-02-15 A study of affecting the recovery of Chinese patients with Bell palsy Zhang, Hongbo Du, Haixia Qian, Mingjing Wang, Yu Zhou, Shenghua Chen, Jing Wan, Haitong Yang, Jiehong Medicine (Baltimore) Research Article We explored the risk factors for preventing recovery of Bell palsy (BP) in Chinese inpatients. Five hundred thirteen patients were included. The two end-points of assessment were the discharge and final follow-up results. Relationship between discharge and baseline: long patients delay (unhealed 4.03 ± 1.16 d vs improved 2.24 ± 1.0 d, P < .001), combined diseases (yes 77.06% vs no 86.71%, P = .01), and early use of acupuncture (yes 47.46% vs no 97.62%, P < .001) were bad factors. Therapeutic factors and discharge: only use of steroids was a positive factor (yes 92.54% vs no 57.30%, P < .001). Binary logistic regression found that early use of steroids was a favorable factor (P = .001), while early use of acupuncture (P < .001) and long patient delay (P < .001) were adverse factors. Subgroups analysis showed early use of steroids plus antivirals (steroids + antivirals vs antivirals + mecobalamin, P < .001) and early use of steroids plus mecobalamin were good choices (steroids + antivirals vs steroids + mecobalamin, P = .745), while early use of antivirals plus mecobalamin was a bad choice (vs other 2 groups, P < .001). Effect of drug dose and treatment course on discharge: long time use of steroids didn’t mean good efficacy (unhealed 10.80 ± 1.53 d vs improved 10.38 ± 1.21 d, P = .026). Final follow-up results: improved patients were better than that of unhealed at discharge (P < .001). Risk factors of discharge included long patient delay, combined diseases, and early use of acupuncture. Steroids plus antivirals or steroids plus mecobalamin were good choices for treatment. Long time use of steroids didn’t mean good effect. Improved patients at discharge had better results finally. Wolters Kluwer Health 2019-01-25 /pmc/articles/PMC6358322/ /pubmed/30681613 http://dx.doi.org/10.1097/MD.0000000000014244 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle Research Article
Zhang, Hongbo
Du, Haixia
Qian, Mingjing
Wang, Yu
Zhou, Shenghua
Chen, Jing
Wan, Haitong
Yang, Jiehong
A study of affecting the recovery of Chinese patients with Bell palsy
title A study of affecting the recovery of Chinese patients with Bell palsy
title_full A study of affecting the recovery of Chinese patients with Bell palsy
title_fullStr A study of affecting the recovery of Chinese patients with Bell palsy
title_full_unstemmed A study of affecting the recovery of Chinese patients with Bell palsy
title_short A study of affecting the recovery of Chinese patients with Bell palsy
title_sort study of affecting the recovery of chinese patients with bell palsy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358322/
https://www.ncbi.nlm.nih.gov/pubmed/30681613
http://dx.doi.org/10.1097/MD.0000000000014244
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