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Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China

This study was aimed to estimate the survival rate characteristics of 2887 hepatocellular carcinoma (HCC) patients in the single-center and identify useful prognostic factors to help in the clinical management of patients with HCC. Two thousand eight hundred eighty-seven patients diagnosed with HCC...

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Detalles Bibliográficos
Autores principales: Wang, Chun-yan, Li, Shengmian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358325/
https://www.ncbi.nlm.nih.gov/pubmed/30681563
http://dx.doi.org/10.1097/MD.0000000000014070
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author Wang, Chun-yan
Li, Shengmian
author_facet Wang, Chun-yan
Li, Shengmian
author_sort Wang, Chun-yan
collection PubMed
description This study was aimed to estimate the survival rate characteristics of 2887 hepatocellular carcinoma (HCC) patients in the single-center and identify useful prognostic factors to help in the clinical management of patients with HCC. Two thousand eight hundred eighty-seven patients diagnosed with HCC at the Fourth Hospital of Hebei Medical University, China, between January 2002 and December 2015 were involved. The causes and baseline characteristics were summarized. Median survival time was 9.0 (20.0) months. Overall, HCC patients showed 1-, 2-, 3-, and 5-year survival rates equal to 49.3%, 35.3%, 26.6%, and19.5% respectively. The median survival time of HCC patients first hospitalized in 2009 to 2015 was higher than those in 2002 to 2008. The results showed that the Barcelona clinic liver cancer (BCLC) stage and Tumor size were independent prognostic factors to HCC patients. The survival rate of HCC patients has increased in recent years, but the overall survival rate and the prognosis were poor.
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spelling pubmed-63583252019-02-15 Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China Wang, Chun-yan Li, Shengmian Medicine (Baltimore) Research Article This study was aimed to estimate the survival rate characteristics of 2887 hepatocellular carcinoma (HCC) patients in the single-center and identify useful prognostic factors to help in the clinical management of patients with HCC. Two thousand eight hundred eighty-seven patients diagnosed with HCC at the Fourth Hospital of Hebei Medical University, China, between January 2002 and December 2015 were involved. The causes and baseline characteristics were summarized. Median survival time was 9.0 (20.0) months. Overall, HCC patients showed 1-, 2-, 3-, and 5-year survival rates equal to 49.3%, 35.3%, 26.6%, and19.5% respectively. The median survival time of HCC patients first hospitalized in 2009 to 2015 was higher than those in 2002 to 2008. The results showed that the Barcelona clinic liver cancer (BCLC) stage and Tumor size were independent prognostic factors to HCC patients. The survival rate of HCC patients has increased in recent years, but the overall survival rate and the prognosis were poor. Wolters Kluwer Health 2019-01-25 /pmc/articles/PMC6358325/ /pubmed/30681563 http://dx.doi.org/10.1097/MD.0000000000014070 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Wang, Chun-yan
Li, Shengmian
Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China
title Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China
title_full Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China
title_fullStr Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China
title_full_unstemmed Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China
title_short Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China
title_sort clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: a single center 14 years experience from china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358325/
https://www.ncbi.nlm.nih.gov/pubmed/30681563
http://dx.doi.org/10.1097/MD.0000000000014070
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