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6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer

BACKGROUND: Cancer cells favor the use of less efficient glycolysis rather than mitochondrial oxidative phosphorylation to metabolize glucose, even in oxygen-rich conditions, a distinct metabolic alteration named the Warburg effect or aerobic glycolysis. In adult cells, bifunctional 6-phosphofructo-...

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Detalles Bibliográficos
Autores principales:	Yi, Mei, Ban, Yuanyuan, Tan, Yixin, Xiong, Wei, Li, Guiyuan, Xiang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358545/ https://www.ncbi.nlm.nih.gov/pubmed/30553771 http://dx.doi.org/10.1016/j.molmet.2018.11.013

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