Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease

OBJECTIVE: Congenital heart disease (CHD) is the most frequent birth defect worldwide. The number of adult patients with CHD, now referred to as ACHD, is increasing with improved surgical and treatment interventions. However the mechanisms whereby ACHD predisposes patients to heart dysfunction are s...

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Detalles Bibliográficos
Autores principales: Wilmanns, Julia C., Pandey, Raghav, Hon, Olivia, Chandran, Anjana, Schilling, Jan M., Forte, Elvira, Wu, Qizhu, Cagnone, Gael, Bais, Preeti, Philip, Vivek, Coleman, David, Kocalis, Heidi, Archer, Stuart K., Pearson, James T., Ramialison, Mirana, Heineke, Joerg, Patel, Hemal H., Rosenthal, Nadia A., Furtado, Milena B., Costa, Mauro W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358551/
https://www.ncbi.nlm.nih.gov/pubmed/30482476
http://dx.doi.org/10.1016/j.molmet.2018.11.002

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