Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism

Hundreds of genetic variants have been associated with Body Mass Index (BMI) through genome-wide association studies (GWAS) using observational cohorts. However, the genetic contribution to efficient weight loss in response to dietary intervention remains unknown. We perform a GWAS in two large low-...

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Detalles Bibliográficos
Autores principales: Valsesia, Armand, Wang, Qiao-Ping, Gheldof, Nele, Carayol, Jérôme, Ruffieux, Hélène, Clark, Teleri, Shenton, Victoria, Oyston, Lisa J., Lefebvre, Gregory, Metairon, Sylviane, Chabert, Christian, Walter, Ondine, Mironova, Polina, Lau, Paulina, Descombes, Patrick, Viguerie, Nathalie, Langin, Dominique, Harper, Mary-Ellen, Astrup, Arne, Saris, Wim H., Dent, Robert, Neely, Greg G., Hager, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358625/
https://www.ncbi.nlm.nih.gov/pubmed/30710084
http://dx.doi.org/10.1038/s41467-019-08492-8

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