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Elucidation of Vasodilation Response and Structure Activity Relationships of N(2),N(4)-Disubstituted Quinazoline 2,4-Diamines in a Rat Pulmonary Artery Model

Pulmonary arterial hypertension (PAH) is a rare and progressive disease arising from various etiologies and pathogenesis. PAH decreases life expectancy due to pulmonary vascular remodeling, elevation of mean pulmonary arterial pressure, and ultimately progresses to heart failure. While clinical trea...

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Detalles Bibliográficos
Autores principales:	Paracha, Tamkeen Urooj, Pobsuk, Nattakarn, Salaloy, Nattapas, Suphakun, Praphasri, Pekthong, Dumrongsak, Hannongbua, Supa, Choowongkomon, Kiattawee, Khorana, Nantaka, Temkitthawon, Prapapan, Ingkaninan, Kornkanok, Gleeson, M. Paul, Chootip, Krongkarn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358775/ https://www.ncbi.nlm.nih.gov/pubmed/30646523 http://dx.doi.org/10.3390/molecules24020281

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