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Searching for Chymase Inhibitors among Chamomile Compounds Using a Computational-Based Approach

Inhibitors of chymase have good potential to provide a novel therapeutic approach for the treatment of cardiovascular diseases. We used a computational approach based on pharmacophore modeling, docking, and molecular dynamics simulations to evaluate the potential ability of 13 natural compounds from...

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Detalles Bibliográficos
Autores principales:	Dubey, Amit, Dotolo, Serena, Ramteke, Pramod W., Facchiano, Angelo, Marabotti, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358779/ https://www.ncbi.nlm.nih.gov/pubmed/30583487 http://dx.doi.org/10.3390/biom9010005

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