Network-Based Assessment of Adverse Drug Reaction Risk in Polypharmacy Using High-Throughput Screening Data

The risk of adverse drug reactions increases in a polypharmacology setting. High-throughput drug screening with transcriptomics applied to human cells has shown that drugs have effects on several molecular pathways, and these affected pathways may be predictive proxy for adverse drug reactions. Depe...

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Detalles Bibliográficos
Autores principales: de Anda-Jáuregui, Guillermo, Guo, Kai, Hur, Junguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358820/
https://www.ncbi.nlm.nih.gov/pubmed/30658437
http://dx.doi.org/10.3390/ijms20020386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358820/
https://www.ncbi.nlm.nih.gov/pubmed/30658437
http://dx.doi.org/10.3390/ijms20020386

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