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Towards Unraveling the Histone Code by Fragment Blind Docking

Histones serve as protein spools for winding the DNA in the nucleosome. High variability of their post-translational modifications result in a unique code system often responsible for the pathomechanisms of epigenetics-based diseases. Decoding is performed by reader proteins via complex formation wi...

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Detalles Bibliográficos
Autores principales: Bálint, Mónika, Horváth, István, Mészáros, Nikolett, Hetényi, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358888/
https://www.ncbi.nlm.nih.gov/pubmed/30669446
http://dx.doi.org/10.3390/ijms20020422