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Fumaric Acids Directly Influence Gene Expression of Neuroprotective Factors in Rodent Microglia
Dimethylfumarate (DMF) has been approved the for treatment of relapsing-remitting multiple sclerosis. The mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood, notably for brain resident cells. Therefore we investigated potential dire...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358967/ https://www.ncbi.nlm.nih.gov/pubmed/30650518 http://dx.doi.org/10.3390/ijms20020325 |