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Fumaric Acids Directly Influence Gene Expression of Neuroprotective Factors in Rodent Microglia

Dimethylfumarate (DMF) has been approved the for treatment of relapsing-remitting multiple sclerosis. The mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood, notably for brain resident cells. Therefore we investigated potential dire...

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Detalles Bibliográficos
Autores principales: Kronenberg, Jessica, Pars, Kaweh, Brieskorn, Marina, Prajeeth, Chittappen K., Heckers, Sandra, Schwenkenbecher, Philipp, Skripuletz, Thomas, Pul, Refik, Pavlou, Andreas, Stangel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358967/
https://www.ncbi.nlm.nih.gov/pubmed/30650518
http://dx.doi.org/10.3390/ijms20020325