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Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers

This study aimed to design phosphatidylcholine (PC)-based solid dispersion (SD) systems for enhancing the apparent aqueous solubility and dissolution of celecoxib (CLC), a selective cyclooxygenase-2 inhibitor with a highly hydrophobic property. Although PC-based dispersion formulations considerably...

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Detalles Bibliográficos
Autores principales:	Jo, Kanghee, Cho, Jae Min, Lee, Hyunjoo, Kim, Eun Kyung, Kim, Hong Chul, Kim, Hyeongmin, Lee, Jaehwi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358979/ https://www.ncbi.nlm.nih.gov/pubmed/30577564 http://dx.doi.org/10.3390/pharmaceutics11010001

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