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The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide

The endoplasmic reticulum (ER) chaperone protein, calreticulin (CRT), is essential for proper glycoprotein folding and maintaining cellular calcium homeostasis. During ER stress, CRT is overexpressed as part of the unfolded protein response (UPR). In addition, CRT can be released as a damage-associa...

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Detalles Bibliográficos
Autores principales: Pandya, Unnati M., Egbuta, Chinaza, Abdullah Norman, Trefa M., Chiang, Chih-Yuan (Edward), Wiersma, Valerie R., Panchal, Rekha G., Bremer, Edwin, Eggleton, Paul, Gold, Leslie I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359024/
https://www.ncbi.nlm.nih.gov/pubmed/30669362
http://dx.doi.org/10.3390/ijms20020408