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The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide
The endoplasmic reticulum (ER) chaperone protein, calreticulin (CRT), is essential for proper glycoprotein folding and maintaining cellular calcium homeostasis. During ER stress, CRT is overexpressed as part of the unfolded protein response (UPR). In addition, CRT can be released as a damage-associa...
Autores principales: | Pandya, Unnati M., Egbuta, Chinaza, Abdullah Norman, Trefa M., Chiang, Chih-Yuan (Edward), Wiersma, Valerie R., Panchal, Rekha G., Bremer, Edwin, Eggleton, Paul, Gold, Leslie I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359024/ https://www.ncbi.nlm.nih.gov/pubmed/30669362 http://dx.doi.org/10.3390/ijms20020408 |
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