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HDAC8 Inhibitor WK2-16 Therapeutically Targets Lipopolysaccharide-Induced Mouse Model of Neuroinflammation and Microglial Activation

Glial activation and neuroinflammatory processes play important roles in the pathogenesis of brain abscess and neurodegenerative diseases. Activated glial cells can secrete various proinflammatory cytokines and neurotoxic mediators, which contribute to the exacerbation of neuronal cell death. The in...

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Detalles Bibliográficos
Autores principales:	Lin, Fan-Li, Yen, Jing-Lun, Kuo, Yu-Cheng, Kang, Jaw-Jou, Cheng, Yu-Wen, Huang, Wei-Jan, Hsiao, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359084/ https://www.ncbi.nlm.nih.gov/pubmed/30669368 http://dx.doi.org/10.3390/ijms20020410

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