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Pharmacokinetic Properties of Arsenic Species after Intravenous and Intragastrical Administration of Arsenic Trioxide Solution in Cynomolgus Macaques Using HPLC-ICP-MS

A rapid and sensitive method was established for arsenic (As) speciation based on high performance liquid chromatography coupled to inductively coupled plasma mass spectrometry (HPLC-ICP-MS). This method was validated for the quantification of four arsenic species, including arsenite (As(III)), arse...

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Detalles Bibliográficos
Autores principales: Shi, Qiaoli, Ju, Mingyan, Zhu, Xiaoxia, Gan, Hui, Gu, Ruolan, Wu, Zhuona, Meng, Zhiyun, Dou, Guifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359110/
https://www.ncbi.nlm.nih.gov/pubmed/30634677
http://dx.doi.org/10.3390/molecules24020241