Epigenetic Factors in Late-Onset Alzheimer’s Disease: MTHFR and CTH Gene Polymorphisms, Metabolic Transsulfuration and Methylation Pathways, and B Vitamins

DNA methylation and other epigenetic factors are important in the pathogenesis of late-onset Alzheimer’s disease (LOAD). Methylenetetrahydrofolate reductase (MTHFR) gene mutations occur in most elderly patients with memory loss. MTHFR is critical for production of S-adenosyl-l-methionine (SAM), the...

Descripción completa

Detalles Bibliográficos
Autores principales: Román, Gustavo C., Mancera-Páez, Oscar, Bernal, Camilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359124/
https://www.ncbi.nlm.nih.gov/pubmed/30646578
http://dx.doi.org/10.3390/ijms20020319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359124/
https://www.ncbi.nlm.nih.gov/pubmed/30646578
http://dx.doi.org/10.3390/ijms20020319

Ejemplares similares