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Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)(4): Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions

In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf(OTf)(4) was identified as a highly potent catalyst for ”one-pot, three-component” Biginelli reaction. More importantly, it was found that solvent-free conditions, in contrast to solvent-based conditions, could dra...

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Detalles Bibliográficos
Autores principales:	Kong, Rui, Han, Shuai-Bo, Wei, Jing-Ying, Peng, Xiao-Chong, Xie, Zhen-Biao, Gong, Shan-Shan, Sun, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359175/ https://www.ncbi.nlm.nih.gov/pubmed/30669606 http://dx.doi.org/10.3390/molecules24020364

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