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Identification, Characterization, and Optimization of Integrin α(v)β(6)-Targeting Peptides from a One-Bead One-Compound (OBOC) Library: Towards the Development of Positron Emission Tomography (PET) Imaging Agents

The current translation of peptides identified through the one-bead one-compound (OBOC) technology into positron emission tomography (PET) imaging agents is a slow process, with a major delay between ligand identification and subsequent lead optimization. This work aims to streamline the development...

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Detalles Bibliográficos
Autores principales: Tang, Yng (Sarah) C., Davis, Ryan A., Ganguly, Tanushree, Sutcliffe, Julie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359284/
https://www.ncbi.nlm.nih.gov/pubmed/30654483
http://dx.doi.org/10.3390/molecules24020309