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Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan

A pattern of natural killer cell (NK cell) heterogeneity determines proliferative and functional responses to activating stimuli in individuals. Obtaining the progeny of a single cell by cloning the original population is one of the ways to study NK cell heterogeneity. In this work, we sorted single...

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Detalles Bibliográficos
Autores principales:	Streltsova, Maria A., Erokhina, Sofya A., Kanevskiy, Leonid M., Grechikhina, Maria V., Kobyzeva, Polina A., Lee, Dean A., Telford, William G., Sapozhnikov, Alexander M., Kovalenko, Elena I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359338/ https://www.ncbi.nlm.nih.gov/pubmed/30669565 http://dx.doi.org/10.3390/ijms20020443

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