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A Computational Method to Propose Mutations in Enzymes Based on Structural Signature Variation (SSV)

With the use of genetic engineering, modified and sometimes more efficient enzymes can be created for different purposes, including industrial applications. However, building modified enzymes depends on several in vitro experiments, which may result in the process being expensive and time-consuming....

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Detalles Bibliográficos
Autores principales: Mariano, Diego César Batista, Santos, Lucianna Helene, Machado, Karina dos Santos, Werhli, Adriano Velasque, de Lima, Leonardo Henrique França, de Melo-Minardi, Raquel Cardoso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359350/
https://www.ncbi.nlm.nih.gov/pubmed/30650542
http://dx.doi.org/10.3390/ijms20020333