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Enhanced Delivery of Imatinib into Vaginal Mucosa via a New Positively Charged Nanocrystal-Loaded in Situ Hydrogel Formulation for Treatment of Cervical Cancer

The present study was carried out to investigate the potential of cationic functionalization on imatinib nanocrystals to improve the mucoadhesiveness and, thus, delivery to the lesion of cervicovaginal tumors. Amino-group-functionalized imatinib nanocrystals (NC@PDA-NH(2)) were prepared with near-sp...

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Detalles Bibliográficos
Autores principales:	Ci, Li-qian, Huang, Zhi-gang, Lv, Feng-mei, Wang, Jun, Feng, Ling-lin, Sun, Feng, Cao, Shui-juan, Liu, Zhe-peng, Liu, Yu, Wei, Gang, Lu, Wei-yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359353/ https://www.ncbi.nlm.nih.gov/pubmed/30621141 http://dx.doi.org/10.3390/pharmaceutics11010015

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