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Pharmacokinetic Simulations of Intravitreal Biologicals: Aspects of Drug Delivery to the Posterior and Anterior Segments

Biologicals are important ocular drugs that are be delivered using monthly and bimonthly intravitreal injections to treat retinal diseases, such as age-related macular degeneration. Long acting delivery systems are needed for prolongation of their dosing interval. Intravitreal biologicals are elimin...

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Detalles Bibliográficos
Autores principales:	Rimpelä, Anna-Kaisa, Kiiski, Iiro, Deng, Feng, Kidron, Heidi, Urtti, Arto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359489/ https://www.ncbi.nlm.nih.gov/pubmed/30598037 http://dx.doi.org/10.3390/pharmaceutics11010009

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