Cargando…

Modulatory Effect of Guinep (Melicoccus bijugatus Jacq) Fruit Pulp Extract on Isoproterenol-Induced Myocardial Damage in Rats. Identification of Major Metabolites Using High Resolution UHPLC Q-Orbitrap Mass Spectrometry

Guinep is traditionally used in the management of cardiovascular ailments. This study aims to evaluate its medicinal constituents and effects in the management of myocardial injury in an experimental isoproterenol (ISO) rat model. Sprague-Dawley rats were randomly assigned to four groups: Group 1 wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nwokocha, Chukwuemeka R., Warren, Isheba, Palacios, Javier, Simirgiotis, Mario, Nwokocha, Magdalene, Harrison, Sharon, Thompson, Rory, Paredes, Adrian, Bórquez, Jorge, Lavado, Astrid, Cifuentes, Fredi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359499/ https://www.ncbi.nlm.nih.gov/pubmed/30634603 http://dx.doi.org/10.3390/molecules24020235

Ejemplares similares

Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats
por: Nwokocha, Chukwuemeka R., et al.
Publicado: (2020)

Polyphenolic Composition and Hypotensive Effects of Parastrephia quadrangularis (Meyen) Cabrera in Rat
por: Cifuentes, Fredi, et al.
Publicado: (2019)

A comparative study of the effect of some nutritional medicinal plants effect on lead accumulation in the liver following different modes of administration
por: Nwokocha, Chukwuemeka, et al.
Publicado: (2014)

8-Oxo-9-Dihydromakomakine Isolated from Aristotelia chilensis Induces Vasodilation in Rat Aorta: Role of the Extracellular Calcium Influx
por: Cifuentes, Fredi, et al.
Publicado: (2018)

Metabolomic Profiling of Mango (Mangifera indica Linn) Leaf Extract and Its Intestinal Protective Effect and Antioxidant Activity in Different Biological Models
por: Ybañez-Julca, Roberto O., et al.
Publicado: (2020)

Novel Oxime Synthesized from a Natural Product of Senecio nutans SCh. Bip. (Asteraceae) Enhances Vascular Relaxation in Rats by an Endothelium-Independent Mechanism
por: Palacios, Javier, et al.
Publicado: (2022)

Investigation of effects of time of measurement and modes of administration on cadmium accumulation in rat liver under some medicinal plants food supplemented diet
por: Nwokocha, Chukwuemeka R., et al.
Publicado: (2014)

Mulinum crassifolium Phil; Two New Mulinanes, Gastroprotective Activity and Metabolomic Analysis by UHPLC-Orbitrap Mass Spectrometry
por: Areche, Carlos, et al.
Publicado: (2019)

Comparative study on the hepatoprotection to heavy metals of Zingiber officinale
por: Nwokocha, Chukwuemeka R., et al.
Publicado: (2012)

Aristoteline, an Indole-Alkaloid, Induces Relaxation by Activating Potassium Channels and Blocking Calcium Channels in Isolated Rat Aorta
por: Romero, Fernando, et al.
Publicado: (2019)

Fast Detection of Phenolic Compounds in Extracts of Easter Pears (Pyrus communis) from the Atacama Desert by Ultrahigh-Performance Liquid Chromatography and Mass Spectrometry (UHPLC–Q/Orbitrap/MS/MS)
por: Simirgiotis, Mario J., et al.
Publicado: (2016)

Comparative analysis on the effect of palm oil (Elaeis guineensis) in reducing cadmium and lead accumulation in liver of Wistar rats
por: Nwokocha, Chukwuemeka R., et al.
Publicado: (2012)

Antioxidant, Gastroprotective, Cytotoxic Activities and UHPLC PDA-Q Orbitrap Mass Spectrometry Identification of Metabolites in Baccharis grisebachii Decoction
por: Gómez, Jessica, et al.
Publicado: (2019)

UHPLC–Q/Orbitrap/MS/MS fingerprinting and antitumoral effects of Prosopis strombulifera (LAM.) BENTH. queous extract on allograft colorectal and melanoma cancer models
por: Persia, Fabio Andrés, et al.
Publicado: (2020)

UHPLC–Q/Orbitrap/MS/MS Fingerprinting, Free Radical Scavenging, and Antimicrobial Activity of Tessaria absinthiodes (Hook. & Arn.) DC. (Asteraceae) Lyophilized Decoction from Argentina and Chile
por: Gómez, Jessica, et al.
Publicado: (2019)

UHPLC-ESI-ORBITRAP-MS analysis of the native Mapuche medicinal plant palo negro (Leptocarpha rivularis DC. – Asteraceae) and evaluation of its antioxidant and cholinesterase inhibitory properties
por: Jiménez-González, Andrea, et al.
Publicado: (2018)

Analysis of Carotenoids in Haloarchaea Species from Atacama Saline Lakes by High Resolution UHPLC-Q-Orbitrap-Mass Spectrometry: Antioxidant Potential and Biological Effect on Cell Viability
por: Lizama, Catherine, et al.
Publicado: (2021)

Phenolic Compounds in Chilean Mistletoe (Quintral, Tristerix tetrandus) Analyzed by UHPLC–Q/Orbitrap/MS/MS and Its Antioxidant Properties
por: Simirgiotis, Mario J., et al.
Publicado: (2016)

Salinization and wastewater effects on the growth and some cell contents of Scenedesmus bijugatus
por: Al-Enazi, Nouf Mohammed
Publicado: (2020)

In Vitro Anthelmintic Evaluation of Gliricidia sepium, Leucaena leucocephala, and Pithecellobium dulce: Fingerprint Analysis of Extracts by UHPLC-Orbitrap Mass Spectrometry
por: Romero, Néstor, et al.
Publicado: (2020)

Treatment of Rats with Apocynin Has Considerable Inhibitory Effects on Arylamine N-Acetyltransferase Activity in the Liver
por: Francis, Sheena, et al.
Publicado: (2016)

Modulatory effect of semelil (ANGIPARS™) on isoproterenol induced cardiac injury
por: Joukar, Siyavash, et al.
Publicado: (2013)

Chemical Fingerprinting and Biological Evaluation of the Endemic Chilean Fruit Greigia sphacelata (Ruiz and Pav.) Regel (Bromeliaceae) by UHPLC-PDA-Orbitrap-Mass Spectrometry
por: Barrientos, Ruth E., et al.
Publicado: (2020)

Pharmacokinetics and Metabolism Research of Shenkang Injection in Rats Based on UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS
por: Jiang, Xiaofang, et al.
Publicado: (2020)

Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta
por: Cifuentes, Fredi, et al.
Publicado: (2020)

May Measurement Month 2019: an analysis of blood pressure screening results from Jamaica
por: Nwokocha, Magdalene, et al.
Publicado: (2021)

Experimental malaria: the in vitro and in vivo blood pressure paradox
por: Nwokocha, CR, et al.
Publicado: (2012)

Chemical Fingerprinting, Isolation and Characterization of Polyphenol Compounds from Heliotropium taltalense (Phil.) I.M. Johnst and Its Endothelium-Dependent Vascular Relaxation Effect in Rat Aorta
por: Barrientos, Ruth E., et al.
Publicado: (2020)

Chilean Rhubarb, Gunnera tinctoria (Molina) Mirb. (Gunneraceae): UHPLC-ESI-Orbitrap-MS Profiling of Aqueous Extract and its Anti-Helicobacter pylori Activity
por: Hebel-Gerber, Sonja, et al.
Publicado: (2021)

Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats
por: Palacios, Javier, et al.
Publicado: (2018)

Maca extracts and estrogen replacement therapy in ovariectomized rats exposed at high altitude
por: Ybañez‐Julca, Roberto O., et al.
Publicado: (2020)

High resolution UHPLC-MS characterization and isolation of main compounds from the antioxidant medicinal plant Parastrephia lucida (Meyen)
por: Echiburu-Chau, Carlos, et al.
Publicado: (2017)

UHPLC-MS Metabolome Fingerprinting: The Isolation of Main Compounds and Antioxidant Activity of the Andean Species Tetraglochin ameghinoi (Speg.) Speg.
por: Luna, Lorena, et al.
Publicado: (2018)

UHPLC-MS Phenolic Fingerprinting, Aorta Endothelium Relaxation Effect, Antioxidant, and Enzyme Inhibition Activities of Azara dentata Ruiz & Pav Berries
por: Ramos, Lucia Cuesta, et al.
Publicado: (2023)

Identification of Phenolic Compounds from Hancornia speciosa (Apocynaceae) Leaves by UHPLC Orbitrap-HRMS
por: Bastos, Katherine Xavier, et al.
Publicado: (2017)

Identification of the metabolites of isochlorogenic acid A in rats by UHPLC-Q-Exactive Orbitrap MS
por: Gong, Kaiyan, et al.
Publicado: (2020)

In Vivo Antihypertensive Activity and UHPLC-Orbitrap-HRMS Profiling of Cuphea ignea A. DC.
por: Ismail, Walaa M., et al.
Publicado: (2022)

Study on Pharmacokinetics and Metabolic Profiles of Novel Potential PLK-1 Inhibitors by UHPLC-MS/MS Combined with UHPLC-Q-Orbitrap/HRMS
por: Wang, Lin, et al.
Publicado: (2023)

Antiseptic Activity of Ethnomedicinal Xuebijing Revealed by the Metabolomics Analysis Using UHPLC-Q-Orbitrap HRMS
por: Zuo, Lihua, et al.
Publicado: (2018)

Analysis of Isoflavones in Pueraria by UHPLC-Q-Orbitrap HRMS and Study on α-Glucosidase Inhibitory Activity
por: Yang, Yan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_17i82blqqtbha77kdrp1p3bgqu