Nanotoxicologic Effects of PLGA Nanoparticles Formulated with a Cell-Penetrating Peptide: Searching for a Safe pDNA Delivery System for the Lungs

The use of cell-penetrating peptides (CPPs) in combination with nanoparticles (NPs) shows great potential for intracellular delivery of DNA. Currently, its application is limited due to the potential toxicity and unknown long-term side effects. In this study NPs prepared using a biodegradable polyme...

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Detalles Bibliográficos
Autores principales: Gomes dos Reis, Larissa, Lee, Wing-Hin, Svolos, Maree, Moir, Lyn Margaret, Jaber, Rima, Windhab, Norbert, Young, Paul Michael, Traini, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359528/
https://www.ncbi.nlm.nih.gov/pubmed/30609825
http://dx.doi.org/10.3390/pharmaceutics11010012

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