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Effects of CD4 Binding on Conformational Dynamics, Molecular Motions, and Thermodynamics of HIV-1 gp120

Human immunodeficiency virus type-1 (HIV-1) infection is triggered by its envelope (Env) glycoprotein gp120 binding to the host-cell receptor CD4. Although structures of Env/gp120 in the liganded state are known, detailed information about dynamics of the liganded gp120 has remained elusive. Two str...

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Detalles Bibliográficos
Autores principales:	Li, Yi, Deng, Lei, Yang, Li-Quan, Sang, Peng, Liu, Shu-Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359530/ https://www.ncbi.nlm.nih.gov/pubmed/30634692 http://dx.doi.org/10.3390/ijms20020260

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