Cargando…

Glutamine Addiction and Therapeutic Strategies in Lung Cancer

Lung cancer cells are well-documented to rewire their metabolism and energy production networks to support rapid survival and proliferation. This metabolic reorganization has been recognized as a hallmark of cancer. The increased uptake of glucose and the increased activity of the glycolytic pathway...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanhove, Karolien, Derveaux, Elien, Graulus, Geert-Jan, Mesotten, Liesbet, Thomeer, Michiel, Noben, Jean-Paul, Guedens, Wanda, Adriaensens, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359540/ https://www.ncbi.nlm.nih.gov/pubmed/30634602 http://dx.doi.org/10.3390/ijms20020252

Ejemplares similares

The Metabolic Landscape of Lung Cancer: New Insights in a Disturbed Glucose Metabolism
por: Vanhove, Karolien, et al.
Publicado: (2019)

Changes in Metabolism as a Diagnostic Tool for Lung Cancer: Systematic Review
por: Mariën, Hanne, et al.
Publicado: (2022)

Unraveling the Rewired Metabolism in Lung Cancer Using Quantitative NMR Metabolomics
por: Vanhove, Karolien, et al.
Publicado: (2022)

Correlations between the metabolic profile and (18)F-FDG-Positron Emission Tomography-Computed Tomography parameters reveal the complexity of the metabolic reprogramming within lung cancer patients
por: Vanhove, Karolien, et al.
Publicado: (2019)

Detection of Lung Cancer via Blood Plasma and (1)H-NMR Metabolomics: Validation by a Semi-Targeted and Quantitative Approach Using a Protein-Binding Competitor
por: Derveaux, Elien, et al.
Publicado: (2021)

NMR-Metabolomics Reveals a Metabolic Shift after Surgical Resection of Non-Small Cell Lung Cancer
por: Derveaux, Elien, et al.
Publicado: (2023)

Plausibility and redundancy analysis to select FDG‐PET textural features in non‐small cell lung cancer
por: Pfaehler, Elisabeth, et al.
Publicado: (2021)

Repeatability of two semi-automatic artificial intelligence approaches for tumor segmentation in PET
por: Pfaehler, Elisabeth, et al.
Publicado: (2021)

Nanobodies for the Early Detection of Ovarian Cancer
por: Tran, Lan-Huong, et al.
Publicado: (2022)

Identification of metabolic phenotypes in childhood obesity by (1)H NMR metabolomics of blood plasma
por: Bervoets, Liene, et al.
Publicado: (2018)

Metabolic profiling of type 1 diabetes mellitus in children and adolescents: a case–control study
por: Bervoets, Liene, et al.
Publicado: (2017)

The plasma glutamate concentration as a complementary tool to differentiate benign PET-positive lung lesions from lung cancer
por: Vanhove, K., et al.
Publicado: (2018)

Gamma radiation effects on AG MP-50 cation exchange resin and sulfonated activated carbon for bismuth-213 separation
por: Zhu, Hongshan, et al.
Publicado: (2023)

Enhanced Biosensor Platforms for Detecting the Atherosclerotic Biomarker VCAM1 Based on Bioconjugation with Uniformly Oriented VCAM1-Targeting Nanobodies
por: Ta, Duy Tien, et al.
Publicado: (2016)

Targeting Glutamine Addiction in Gliomas
por: Obara-Michlewska, Marta, et al.
Publicado: (2020)

Rethinking glutamine metabolism and the regulation of glutamine addiction by oncogenes in cancer
por: Ni, Rui, et al.
Publicado: (2023)

Distinct effects of etoposide on glutamine-addicted neuroblastoma
por: Valter, Kadri, et al.
Publicado: (2019)

Therapeutic Potential of Glutamine Pathway in Lung Cancer
por: Tang, Enyu, et al.
Publicado: (2022)

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma
por: Ratnikov, Boris, et al.
Publicado: (2015)

TAp73 is a marker of glutamine addiction in medulloblastoma
por: Niklison-Chirou, Maria Victoria, et al.
Publicado: (2017)

Hopefully devoted to Q: targeting glutamine addiction in cancer
por: Still, Emma R, et al.
Publicado: (2017)

A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer
por: Jin, Haojie, et al.
Publicado: (2020)

Targeting glutamine metabolism as a therapeutic strategy for cancer
por: Jin, Jonghwa, et al.
Publicado: (2023)

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia
por: Nguyen, Tra Ly, et al.
Publicado: (2021)

Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells
por: Smith, Bradley, et al.
Publicado: (2016)

Correction: Hopefully devoted to Q: targeting glutamine addiction in cancer
por: Still, Emma R., et al.
Publicado: (2019)

Glutamine addiction promotes glucose oxidation in triple-negative breast cancer
por: Quek, Lake-Ee, et al.
Publicado: (2022)

Targeting Glutamine Metabolism as an Attractive Therapeutic Strategy for Acute Myeloid Leukemia
por: Xiao, Yan, et al.
Publicado: (2023)

Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction
por: Cetinbas, Naniye, et al.
Publicado: (2014)

Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival
por: Sanchez, Erica L., et al.
Publicado: (2015)

WEE1 inhibition induces glutamine addiction in T-cell acute lymphoblastic leukemia
por: Hu, Juncheng, et al.
Publicado: (2020)

NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function
por: Kumar, Ajay, et al.
Publicado: (2022)

α-Ketoglutaramate—A key metabolite contributing to glutamine addiction in cancer cells
por: Cooper, Arthur J. L., et al.
Publicado: (2022)

Limiting glutamine utilization activates a GCN2/TRAIL-R2/Caspase-8 apoptotic pathway in glutamine-addicted tumor cells
por: Yerbes, Rosario, et al.
Publicado: (2022)

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction
por: Fogal, Valentina, et al.
Publicado: (2014)

Glutamine supplementation
por: Wernerman, Jan
Publicado: (2011)

A clinically attainable dose of L‐asparaginase targets glutamine addiction in lymphoid cell lines
por: Sugimoto, Koichi, et al.
Publicado: (2015)

THU476 Role Of Mitochondrial Sirtuins 3 And 5 On Glutamine Addiction In Prostate Cancer Cell
por: Hasan, Kamrul M, et al.
Publicado: (2023)

Role and therapeutic targeting of glutamine metabolism in non‑small cell lung cancer (Review)
por: Zhou, Lei, et al.
Publicado: (2023)

Metabolic Heterogeneity, Plasticity, and Adaptation to “Glutamine Addiction” in Cancer Cells: The Role of Glutaminase and the GTωA [Glutamine Transaminase—ω-Amidase (Glutaminase II)] Pathway
por: Cooper, Arthur J. L., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bsm9oqfds7vmrtkkgf4albg5a8