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Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells
Obstructive sleep apnea (OSA) affects a significant proportion of the population and is linked to increased rates of cancer development and a worse cancer outcome. OSA is characterized by nocturnal intermittent hypoxia and animal models of OSA-like intermittent hypoxia show increased tumor growth an...
Autores principales: | Martinez, Chloe-Anne, Kerr, Bernadette, Jin, Charley, Cistulli, Peter A., Cook, Kristina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359625/ https://www.ncbi.nlm.nih.gov/pubmed/30669593 http://dx.doi.org/10.3390/ijms20020445 |
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