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Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme
BACKGROUND: In recent years, PD-1/PD-L1 immune checkpoint inhibitors have improved cancer therapy in many tumor types, but no benefit of immune checkpoint therapy has been found in glioblastoma multiforme (GBM). Based on the results of our earlier work, which showed a reduction of PD-L1 expression i...
Autores principales: | Heynckes, Sabrina, Daka, Karam, Franco, Pamela, Gaebelein, Annette, Frenking, Jan Hendrik, Doria-Medina, Roberto, Mader, Irina, Delev, Daniel, Schnell, Oliver, Heiland, Dieter Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359796/ https://www.ncbi.nlm.nih.gov/pubmed/30709339 http://dx.doi.org/10.1186/s12885-019-5308-y |
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