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Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol

OBJECTIVE: To evaluate the safety and effectiveness of NOM (non-operative management) in the treatment of blunt liver trauma, following a standardized treatment protocol. METHODS: All the hemodynamically stable patients with computed tomography (CT) diagnosis of blunt liver trauma underwent NOM. It...

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Autores principales: Brillantino, Antonio, Iacobellis, Francesca, Festa, Patrizio, Mottola, Arianna, Acampora, Ciro, Corvino, Fabio, Del Giudice, Santolo, Lanza, Michele, Armellino, Mariano, Niola, Raffaella, Romano, Luigia, Castriconi, Maurizio, De Palma, Maurizio, Noschese, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360015/
https://www.ncbi.nlm.nih.gov/pubmed/30719466
http://dx.doi.org/10.29252/beat-070107
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author Brillantino, Antonio
Iacobellis, Francesca
Festa, Patrizio
Mottola, Arianna
Acampora, Ciro
Corvino, Fabio
Del Giudice, Santolo
Lanza, Michele
Armellino, Mariano
Niola, Raffaella
Romano, Luigia
Castriconi, Maurizio
De Palma, Maurizio
Noschese, Giuseppe
author_facet Brillantino, Antonio
Iacobellis, Francesca
Festa, Patrizio
Mottola, Arianna
Acampora, Ciro
Corvino, Fabio
Del Giudice, Santolo
Lanza, Michele
Armellino, Mariano
Niola, Raffaella
Romano, Luigia
Castriconi, Maurizio
De Palma, Maurizio
Noschese, Giuseppe
author_sort Brillantino, Antonio
collection PubMed
description OBJECTIVE: To evaluate the safety and effectiveness of NOM (non-operative management) in the treatment of blunt liver trauma, following a standardized treatment protocol. METHODS: All the hemodynamically stable patients with computed tomography (CT) diagnosis of blunt liver trauma underwent NOM. It included strict clinical and laboratory observation, 48-72h contrast enhanced ultrasonography (CEUS) or CT follow-up, a primary angioembolization in case of admission CT evidence of vascular injuries and a secondary angioembolization in presence of vascular injuries signs at follow-up CEUS. RESULTS: 181 patients (85.4%) [55 (30.4%) women and 126 (69.6%) men, median age 39 (range 14–71)] were included. Of these, 63 patients (34.8%) had grade I, 48 patients (26.5%) grade II, 39 patients (21.5%) grade III, 21 patients (11.6%) grade IV and 10 patients (5.5%) grade V liver injuries. The overall success rate of NOM was 96.7% (175/181). There was not significant difference in the success rate between the patients with different liver injuries grade. Morbidity rate was 7.4% (13/175). Major complications (2 bilomas, 1 liver hematoma and 2 liver abscesses) were successfully treated by CEUS or CT guided drainage. Eighteen (18/181) patients (9.9%) underwent angioembolization with successful results. CONCLUSION: Non-operative management of blunt liver trauma represents a safe and effective treatment for both minor and severe injuries, achieving an high success rate and an acceptable morbidity rate. The angiographic study with embolization, although required only in selected cases of vascular injuries, represents a fundamental therapeutic option in a significant percentage of patients.
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spelling pubmed-63600152019-02-04 Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol Brillantino, Antonio Iacobellis, Francesca Festa, Patrizio Mottola, Arianna Acampora, Ciro Corvino, Fabio Del Giudice, Santolo Lanza, Michele Armellino, Mariano Niola, Raffaella Romano, Luigia Castriconi, Maurizio De Palma, Maurizio Noschese, Giuseppe Bull Emerg Trauma Original Article OBJECTIVE: To evaluate the safety and effectiveness of NOM (non-operative management) in the treatment of blunt liver trauma, following a standardized treatment protocol. METHODS: All the hemodynamically stable patients with computed tomography (CT) diagnosis of blunt liver trauma underwent NOM. It included strict clinical and laboratory observation, 48-72h contrast enhanced ultrasonography (CEUS) or CT follow-up, a primary angioembolization in case of admission CT evidence of vascular injuries and a secondary angioembolization in presence of vascular injuries signs at follow-up CEUS. RESULTS: 181 patients (85.4%) [55 (30.4%) women and 126 (69.6%) men, median age 39 (range 14–71)] were included. Of these, 63 patients (34.8%) had grade I, 48 patients (26.5%) grade II, 39 patients (21.5%) grade III, 21 patients (11.6%) grade IV and 10 patients (5.5%) grade V liver injuries. The overall success rate of NOM was 96.7% (175/181). There was not significant difference in the success rate between the patients with different liver injuries grade. Morbidity rate was 7.4% (13/175). Major complications (2 bilomas, 1 liver hematoma and 2 liver abscesses) were successfully treated by CEUS or CT guided drainage. Eighteen (18/181) patients (9.9%) underwent angioembolization with successful results. CONCLUSION: Non-operative management of blunt liver trauma represents a safe and effective treatment for both minor and severe injuries, achieving an high success rate and an acceptable morbidity rate. The angiographic study with embolization, although required only in selected cases of vascular injuries, represents a fundamental therapeutic option in a significant percentage of patients. Shiraz University of Medical Sciences 2019-01 /pmc/articles/PMC6360015/ /pubmed/30719466 http://dx.doi.org/10.29252/beat-070107 Text en © 2019 Trauma Research Center, Shiraz University of Medical Sciences Bulletin of Emergency And Trauma articles are published under a Creative Commons license. (http://creativecommons.org/licenses/) Mandated authors will be offered CC-BY; all other authors will choose between CC-BY, CC-BY-NC and CC-BY-NC-ND.
spellingShingle Original Article
Brillantino, Antonio
Iacobellis, Francesca
Festa, Patrizio
Mottola, Arianna
Acampora, Ciro
Corvino, Fabio
Del Giudice, Santolo
Lanza, Michele
Armellino, Mariano
Niola, Raffaella
Romano, Luigia
Castriconi, Maurizio
De Palma, Maurizio
Noschese, Giuseppe
Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol
title Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol
title_full Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol
title_fullStr Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol
title_full_unstemmed Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol
title_short Non-Operative Management of Blunt Liver Trauma: Safety, Efficacy and Complications of a Standardized Treatment Protocol
title_sort non-operative management of blunt liver trauma: safety, efficacy and complications of a standardized treatment protocol
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360015/
https://www.ncbi.nlm.nih.gov/pubmed/30719466
http://dx.doi.org/10.29252/beat-070107
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