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Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity

We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of ho...

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Autores principales: Schwade, Jan-Niclas, Haftel, Lior, Rühe, Lars, Endmann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360061/
https://www.ncbi.nlm.nih.gov/pubmed/30800484
http://dx.doi.org/10.1155/2019/7381597
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author Schwade, Jan-Niclas
Haftel, Lior
Rühe, Lars
Endmann, Matthias
author_facet Schwade, Jan-Niclas
Haftel, Lior
Rühe, Lars
Endmann, Matthias
author_sort Schwade, Jan-Niclas
collection PubMed
description We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of hospitalization, the patient developed tremor, ataxia, and rigor. Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. The child recovered completely after hospitalization for nearly 2 weeks.
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spelling pubmed-63600612019-02-24 Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity Schwade, Jan-Niclas Haftel, Lior Rühe, Lars Endmann, Matthias Case Rep Pediatr Case Report We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of hospitalization, the patient developed tremor, ataxia, and rigor. Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. The child recovered completely after hospitalization for nearly 2 weeks. Hindawi 2019-01-17 /pmc/articles/PMC6360061/ /pubmed/30800484 http://dx.doi.org/10.1155/2019/7381597 Text en Copyright © 2019 Jan-Niclas Schwade et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Schwade, Jan-Niclas
Haftel, Lior
Rühe, Lars
Endmann, Matthias
Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_full Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_fullStr Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_full_unstemmed Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_short Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
title_sort extrapontine myelinolysis following extreme hypernatremia and hyperosmolarity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360061/
https://www.ncbi.nlm.nih.gov/pubmed/30800484
http://dx.doi.org/10.1155/2019/7381597
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