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Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity
We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of ho...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360061/ https://www.ncbi.nlm.nih.gov/pubmed/30800484 http://dx.doi.org/10.1155/2019/7381597 |
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author | Schwade, Jan-Niclas Haftel, Lior Rühe, Lars Endmann, Matthias |
author_facet | Schwade, Jan-Niclas Haftel, Lior Rühe, Lars Endmann, Matthias |
author_sort | Schwade, Jan-Niclas |
collection | PubMed |
description | We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of hospitalization, the patient developed tremor, ataxia, and rigor. Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. The child recovered completely after hospitalization for nearly 2 weeks. |
format | Online Article Text |
id | pubmed-6360061 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-63600612019-02-24 Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity Schwade, Jan-Niclas Haftel, Lior Rühe, Lars Endmann, Matthias Case Rep Pediatr Case Report We present a case of a nearly 3-year-old girl who was admitted to hospital due to severe hypernatremia (196 mmol/l). Her medical history included central hypothyreosis and growth hormone deficiency. Rehydration and normalization of sodium was achieved according to guidelines. On the fourth day of hospitalization, the patient developed tremor, ataxia, and rigor. Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. The child recovered completely after hospitalization for nearly 2 weeks. Hindawi 2019-01-17 /pmc/articles/PMC6360061/ /pubmed/30800484 http://dx.doi.org/10.1155/2019/7381597 Text en Copyright © 2019 Jan-Niclas Schwade et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Schwade, Jan-Niclas Haftel, Lior Rühe, Lars Endmann, Matthias Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity |
title | Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity |
title_full | Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity |
title_fullStr | Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity |
title_full_unstemmed | Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity |
title_short | Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity |
title_sort | extrapontine myelinolysis following extreme hypernatremia and hyperosmolarity |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360061/ https://www.ncbi.nlm.nih.gov/pubmed/30800484 http://dx.doi.org/10.1155/2019/7381597 |
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