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Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer

Objective: Apolipoprotein A1 (ApoA1) is remarkably decreased in serum and ovarian tissues of ovarian cancer patients. ApoA1 and ApoA1 mimetic peptides can sequestrate pro-inflammatory phospholipids, some of which are known to activate a variety of oncogenic pathways. Besides, more intrinsic anti-tum...

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Detalles Bibliográficos
Autores principales:	Marinho, Aline T., Lu, Haonan, Pereira, Sofia A., Monteiro, Emília, Gabra, Hani, Recchi, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360149/ https://www.ncbi.nlm.nih.gov/pubmed/30745873 http://dx.doi.org/10.3389/fphar.2018.01524

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