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CircFunBase: a database for functional circular RNAs

Increasing evidence reveals that circular RNAs (circRNAs) are widespread in eukaryotes and play important roles in diverse biological processes. However, a comprehensive functionally annotated circRNA database is still lacking. CircFunBase is a web-accessible database that aims to provide a high-qua...

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Detalles Bibliográficos
Autores principales: Meng, Xianwen, Hu, Dahui, Zhang, Peijing, Chen, Qi, Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360206/
https://www.ncbi.nlm.nih.gov/pubmed/30715276
http://dx.doi.org/10.1093/database/baz003
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author Meng, Xianwen
Hu, Dahui
Zhang, Peijing
Chen, Qi
Chen, Ming
author_facet Meng, Xianwen
Hu, Dahui
Zhang, Peijing
Chen, Qi
Chen, Ming
author_sort Meng, Xianwen
collection PubMed
description Increasing evidence reveals that circular RNAs (circRNAs) are widespread in eukaryotes and play important roles in diverse biological processes. However, a comprehensive functionally annotated circRNA database is still lacking. CircFunBase is a web-accessible database that aims to provide a high-quality functional circRNA resource including experimentally validated and computationally predicted functions. The current version of CircFunBase documents more than 7000 manually curated functional circRNA entries, mainly including Homo sapiens, Mus musculus etc. CircFunBase provides visualized circRNA-miRNA interaction networks. In addition, a genome browser is provided to visualize the genome context of circRNAs. As a biological information platform for circRNAs, CircFunBase will contribute for circRNA studies and bridge the gap between circRNAs and their functions.
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spelling pubmed-63602062019-02-08 CircFunBase: a database for functional circular RNAs Meng, Xianwen Hu, Dahui Zhang, Peijing Chen, Qi Chen, Ming Database (Oxford) Database Tool Increasing evidence reveals that circular RNAs (circRNAs) are widespread in eukaryotes and play important roles in diverse biological processes. However, a comprehensive functionally annotated circRNA database is still lacking. CircFunBase is a web-accessible database that aims to provide a high-quality functional circRNA resource including experimentally validated and computationally predicted functions. The current version of CircFunBase documents more than 7000 manually curated functional circRNA entries, mainly including Homo sapiens, Mus musculus etc. CircFunBase provides visualized circRNA-miRNA interaction networks. In addition, a genome browser is provided to visualize the genome context of circRNAs. As a biological information platform for circRNAs, CircFunBase will contribute for circRNA studies and bridge the gap between circRNAs and their functions. Oxford University Press 2019-02-04 /pmc/articles/PMC6360206/ /pubmed/30715276 http://dx.doi.org/10.1093/database/baz003 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Tool
Meng, Xianwen
Hu, Dahui
Zhang, Peijing
Chen, Qi
Chen, Ming
CircFunBase: a database for functional circular RNAs
title CircFunBase: a database for functional circular RNAs
title_full CircFunBase: a database for functional circular RNAs
title_fullStr CircFunBase: a database for functional circular RNAs
title_full_unstemmed CircFunBase: a database for functional circular RNAs
title_short CircFunBase: a database for functional circular RNAs
title_sort circfunbase: a database for functional circular rnas
topic Database Tool
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360206/
https://www.ncbi.nlm.nih.gov/pubmed/30715276
http://dx.doi.org/10.1093/database/baz003
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