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Area under the curve analysis of blood pressure reveals increased spontaneous locomotor activity in SPAK knock‐in mice: relevance for hypotension induced by SPAK inhibition?
SPAK (Ste20/SPS1‐related proline/alanine‐rich kinase) has been recently identified as a protein kinase which targets the electroneutral cation‐coupled chloride cotransporters and it stands out as a target for inhibition in novel anti‐hypertensive agents. From this prospective, any information about...
Autores principales: | Burgess, Kieran, Jovanović, Sofija, Sudhir, Rajni, Jovanović, Aleksandar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360239/ https://www.ncbi.nlm.nih.gov/pubmed/30714348 http://dx.doi.org/10.14814/phy2.13997 |
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