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Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine–Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy

Shallow extravillous trophoblast (EVT) invasion is central to the pathophysiology of many pregnancy complications. Invasion is mediated partially by matrix metalloproteinases (MMPs). MMP-2 is highly expressed in early pregnancy. MMP activity can be regulated by proinflammatory cytokines, which also...

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Detalles Bibliográficos
Autores principales: Lee, Cheuk-Lun, Veerbeek, Jan H.W., Rana, Tirtha K., van Rijn, Bas B., Burton, Graham J., Yung, Hong Wa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360351/
https://www.ncbi.nlm.nih.gov/pubmed/30448406
http://dx.doi.org/10.1016/j.ajpath.2018.10.015