Cargando…
Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine–Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy
Shallow extravillous trophoblast (EVT) invasion is central to the pathophysiology of many pregnancy complications. Invasion is mediated partially by matrix metalloproteinases (MMPs). MMP-2 is highly expressed in early pregnancy. MMP activity can be regulated by proinflammatory cytokines, which also...
Autores principales: | Lee, Cheuk-Lun, Veerbeek, Jan H.W., Rana, Tirtha K., van Rijn, Bas B., Burton, Graham J., Yung, Hong Wa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Investigative Pathology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360351/ https://www.ncbi.nlm.nih.gov/pubmed/30448406 http://dx.doi.org/10.1016/j.ajpath.2018.10.015 |
Ejemplares similares
-
Endoplasmic reticulum stress is induced in the human placenta during labour
por: Veerbeek, J.H.W., et al.
Publicado: (2015) -
Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude
por: Yung, Hong Wa, et al.
Publicado: (2012) -
Endoplasmic reticulum stress in the pathogenesis of early-onset pre-eclampsia
por: Burton, Graham J., et al.
Publicado: (2011) -
Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy
por: Matheson, Hannah, et al.
Publicado: (2015) -
Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors
por: Cheng, Shi-Bin, et al.
Publicado: (2019)