Cargando…

Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration

Recent fate-mapping studies in mice have provided substantial evidence that mature adult hepatocytes are a major source of new hepatocytes after liver injury. In other systems, integrin αvβ8 has a major role in activating transforming growth factor (TGF)-β, a potent inhibitor of hepatocyte prolifera...

Descripción completa

Detalles Bibliográficos
Autores principales: Greenhalgh, Stephen N., Matchett, Kylie P., Taylor, Richard S., Huang, Katherine, Li, John T., Saeteurn, Koy, Donnelly, Mhairi C., Simpson, Eilidh E.M., Pollack, Joshua L., Atakilit, Amha, Simpson, Kenneth J., Maher, Jacquelyn J., Iredale, John P., Sheppard, Dean, Henderson, Neil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360354/
https://www.ncbi.nlm.nih.gov/pubmed/30448409
http://dx.doi.org/10.1016/j.ajpath.2018.10.007