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Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration
Recent fate-mapping studies in mice have provided substantial evidence that mature adult hepatocytes are a major source of new hepatocytes after liver injury. In other systems, integrin αvβ8 has a major role in activating transforming growth factor (TGF)-β, a potent inhibitor of hepatocyte prolifera...
Autores principales: | Greenhalgh, Stephen N., Matchett, Kylie P., Taylor, Richard S., Huang, Katherine, Li, John T., Saeteurn, Koy, Donnelly, Mhairi C., Simpson, Eilidh E.M., Pollack, Joshua L., Atakilit, Amha, Simpson, Kenneth J., Maher, Jacquelyn J., Iredale, John P., Sheppard, Dean, Henderson, Neil C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Investigative Pathology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360354/ https://www.ncbi.nlm.nih.gov/pubmed/30448409 http://dx.doi.org/10.1016/j.ajpath.2018.10.007 |
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