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Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment
The peritoneal fluid of ovarian carcinoma patients promotes cancer cell invasion and metastatic spread with lysophosphatidic acid (LPA) as a potentially crucial mediator. However, the origin of LPA in ascites and the clinical relevance of individual LPA species have not been addressed. Here, we show...
Autores principales: | Reinartz, Silke, Lieber, Sonja, Pesek, Jelena, Brandt, Dominique T., Asafova, Alina, Finkernagel, Florian, Watzer, Bernard, Nockher, Wolfgang Andreas, Nist, Andrea, Stiewe, Thorsten, Jansen, Julia M., Wagner, Uwe, Konzer, Anne, Graumann, Johannes, Grosse, Robert, Worzfeld, Thomas, Müller‐Brüsselbach, Sabine, Müller, Rolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360368/ https://www.ncbi.nlm.nih.gov/pubmed/30353652 http://dx.doi.org/10.1002/1878-0261.12396 |
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